Purpose
     The UMBRELLA kit for photodynamic therapy and fluorescent diagnostics   is intended for visual diagnostics and treatment by a method of photodynamic therapy of colonies of pathological and oncological cells.

The kit is applied independently or together with other therapeutic or surgical laser instruments, laser spectral evaluators and diverse diagnostic instruments in structure of the cabinets of photodynamic therapy in clinics, hospitals and research and development medical establishments.

The complex reputes operation with different types of the PDT-drugs, first of all with high-performance and low-toxic ones, for example, with the Radachlorin photosensitizer.

Device and principle of the operation
     The kit is executed on the basis of a matrix from semiconductor light emitting diodes of heightened brightness and specialized video camera with a specially designed light filter providing authentic registration of a fluorescence. The kit reputes usage of standard means of a signal display of the video map of the camera allowed for medical practice.

The kit powers up a matrix and video camera hardened on supports permitting to direct radiating of a matrix and a field of supervising of the camera on the same zone, for example, surface segment of a skin. A matrix and video camera aggregate by cables to a separate power supply unit, through last the cue on the screen monitor files also.

The matrix contains group (more than 1000) light emitting diodes built - on close-packed on the shaped round surface permitting to focalize (in definite limits) total radiating of collection of diodes of a matrix. The matrix is supplied with cooling vanes. The video camera is executed on the basis of standard vehicle KRS-900 in the optical channel which one the filtering of a visible portion of the spectrum is stipulated, except for area of a fluorescence, for example, 670-680 nm.

The matrix is used for beaming a zone of a pathology previously sensitized by the PDT-drug. Thus the wave length of radiating of light emitting diodes of a matrix should coincide absorption band of the drug. The beaming serves for creation of a necrosis, thus there is an accompanying fluorescence in an exposure zone of the drug accrued in a tissue.

The supervising of an irradiated surface segment with the help of the video camera allows to register a zone of a fluorescence by the way visually of brighter pattern indemnification a background of beaming of a matrix. The zone of a fluorescence meets to a zone of a pathology with heightened accruing of the pdt-drug a procedure of supervising of a fluorescence of a zone of a pathology is diagnostic. It can precede, accompany therapeutic beaming or be executed separately. In the latter case radiation intensity can be reduced by a matrix (power density and energy) concerning therapeutic significances.

Due to a possibility of multiple repetition of a procedure at usage of the Radachlorin photosensitizer (feature of the drug favourably distinguishing it from other photosensitizers) is possible to watch process of diagnostics - therapy in dynamics.

Characteristics

• Radiation condition of a matrix - continuous
• Radiation wavelength of a matrix - 650-670 nm
• A power density of working radiating of a matrix in a focal plan - 30-60 mW/sm2
• Consumed electric power of the vehicle - no more than 20 W
• The floor space of a spot of beaming in a focal plan - 40 sm2
• Focal spacing interval - 20-40 sm
• Overall dimensions of a matrix no more – 300 x 300 mm
• A definition of an oilpainting of a bloom on the shield of a black-and-white monitor with resolution - no more than 2 mms
• A transient time of an operating duty - no more than 5 min.
• Time of continuous operation - till 6 hours
• A supply voltage - 220 In (+/- 10%)
• Frequency of a web - 50 Hz
• Consumed power - no more than 250 VA
• Bulk of kit - no more than 12 kgs
• An average operating time of the vehicle on refusal not less than 1500 hours, average due date of a service of the vehicle - 5 years

The electrosafety of the vehicle conforms the requirements the GOST R 50267.0 and is executed on the class 2 and type of protection BF. The vehicle is thermostable at operation to effect of temperature of ambient air from 10 up to 35oя.

List of standard equipment
     The UMBRELLA kit for photodynamic therapy and fluorescent diagnostics RDFA.944420.001* in structure:

• Power supply unit of kit (RDFA.944421.001) - 1 piece
• The video camera KRS-900 (RDFA.311528.001)** - 1 piece
• LED matrix (RDFA.943635.001) - 1 piece
• Power cord AWM E69326 - 1 piece
• The passport TO and IE (RDFA.944420.001PS) - 1 piece
• Bag for a storage and transportation of kit - 1 piece
• Support LPD24.MN*** - 2 pieces
• Glasses protective**** - 1 piece

* - The video monitor does not enter into a complete set of delivery, is if necessary delivered to the customer the separate payment.
** - The video camera does not enter into the simplified set of delivery.
*** - Acquisition by supports to be made separately, as agreed with the customer.
**** - Acquisition by shielding spectacles to be made separately, as agreed with the customer. The complete set by glasses of other pattern with the similar performances is possible.

For usage of the UMBRELLA kit for photodynamic therapy and fluorescent diagnostics with the personal computer, the problem software permitting maximum effectively is developed to watch dynamics of treatment and diagnostics of the patients.

By the order to be made and the simplified version of a complex is delivered, which one does not include the video camera.